Kylie Vincent's Group
Department of Chemistry,
University of Oxford,
Inorganic Chemistry Laboratory,
South Parks Road, OX1 3QR
kylie.vincent@chem.ox.ac.uk

Kylie Vincent

Professor of Inorganic Chemistry and
Fellow and Tutor in Inorganic Chemistry at Jesus College Oxford and
University Academic Champion for Women in Entrepreneurship

Kylie Vincent is a graduate of the University of Melbourne, Australia (BA/ BSc(Hons), Ph.D. (2004)). Her PhD research was conducted in the group of Stephen Best (University of Melbourne) and involved a 12 month collaborative visit to the group of Chris Pickett (John Innes Centre, Norwich, UK) supported by a Rae and Edith Bennett Travelling Scholarship. She carried out postdoctoral research at the University of Oxford with Fraser Armstrong from 2002-2007 and held an R. J. P. Williams Junior Research Fellowship at Wadham College, Oxford from 2003-2007. In October 2007 she took up a Royal Society University Research Fellowship in the Chemistry Department at Oxford University and a Senior Research Fellowship at Wadham College, Oxford. In October 2008 she was appointed to an RCUK Academic Fellowship in the Chemistry Department and a Senior Research Fellowship at Jesus College Oxford. She was appointed Associate Professor in 2013, and appointed to a full Professorship in 2017. In 2021 she co-founded the spin-out company HydRegen Ltd, and took on a newly-created University role as Academic Champion for Women in Entrepreneurship. Her research interests include mechanistic studies of small molecule activation in biology, and applications of enzymes in chemical synthesis. She teaches in Inorganic Chemistry.View CV

Postdoctoral Scientists

Miguel Ramirez

Miguel is a Postdoctoral Research Associate contributing to the development of the HydRegen technology. He is a graduate of The University of Texas at Austin (BSc) and completed his Ph.D. in Chemical Engineering at Texas A&M University in 2013. Miguel works in the molecular biology and protein engineering efforts required for enzyme preparation, engineering and adaptation to the HydRegen technology. His research interests include the application of proteins for biotechnology and synthetic biology applications.

Rhiannon 'Non' Evans

Non joined the Vincent group in August 2019 as a post-doctoral research associate bringing specialist knowledge of hydrogenases to the group. With expertise in redox enzymes, protein film electrochemistry and molecular biology & genetics, Non is primed to develop the hypotheses around hydrogenase mechanism, coupled with the development of in crystallo IR and spectroelectrochemistry. During her spare time she is actively avoiding injury to be able to one day run a marathon. View CV

Patricia Rodríguez Macía - Glasstone Fellow

Patricia did her undergraduate studies in Chemistry at the University of Alicante (Spain) before moving to Germany for her PhD at the Max Planck Institute for Chemical Energy Conversion (MPI-CEC) with Prof. Lubitz. Her doctoral research focused on employing electrochemistry and infrared spectroscopy to perform mechanistic studies on hydrogenases and bio-inspired synthetic catalysts. After completing her PhD, she joined Prof. DeBeer's group at MPI-CEC to work on carbon monoxide dehydrogenases and other metalloenzymes applying X-ray spectroscopy. Patricia joined the Vincent group in January 2020 as a Postdoctoral Research Associate to contribute to optimisation of immobilization approaches for metalloenzymes and to work on the development of infrared spectroelectrochemical techniques, and was then appointed to a Glasstone Fellowship in October 2021. She is a JRF at Linacre College. She loves travelling and in her free time she enjoys cooking and meeting with friends.View Web

Tim Sudmeier

Tim completed his undergrad degree at Jacobs University Bremen before moving to Oxford for a PhD in the group of Edman Tsang developing novel catalysts for the hydrogen evolution reaction and electrochemical ammonia synthesis. He is interested in using renewable energy to power the chemical industry and is now investigating metalloenzymes and their application in the production of fine chemicals.

DPhil and MSc Students

Sophie Kendall-Price

Sophie (former Part II) is a final year DPhil student at Christ Church. Her research involves the use of infrared spectroelectrochemical techniques in mechanistic studies of NiFe hydrogenases. In her free time, Sophie enjoys playing the double bass, eating Korean food and hiking around the countryside with her dog.

Xu Zhao

Xu Zhao is a final year DPhil student at Exeter College. His work includes but not limited to the application of oxidoreductase and research towards scale-up of the Vincent group's HydRegen technology. He got his bachelor degree in chemical engineering at China University of Petroleum (Beijing, China) and his master degree at University of British Columbia (Canada).

Jiawen Zhang

Jiawen Zhang is a final year DPhil student at Jesus College. His research involves the mechanisms of biocatalytic carbon dioxide reduction. He got his bachelor degree at Tsinghua University, and he got his master degree at University of Sheffield. In his free time, he loves basketball and PC gaming!

Yu Sun

Yu is a final year DPhil student working on metalloenzyme mechanisms.

Shiny Joseph Srinivasan

I am a final year DPhil student at St. Edmund Hall. I received my bachelor's degree in Chemistry from PSG College of Arts and Science, India and then completed my Masters in Chemistry from the National Institute of Technology, Trichy (India). In the Vincent group, I am working in the HydRegen project trying to efficiently recycle the biologically important cofactors in order to be used for industrially significant enzymatic chemical conversions. In my free time, I love to dance, travel and explore new places.

Wangzhe Li

Wangzhe is a final year DPhil student at Lincare College and he completed his BSc degree at Durham University. His research in the Vincent group involves studying NiFe hydrogenases via spectroelectrochemical methods.

Sam (Tin) Lai

Sam is a 3rd year DPhil student whose research focuses on the mechanistic study of [FeFe] Hydrogenase. He got his bachelor degree from Durham University. He loves to play basketball in his free time.

Charlotte Hancox

Charlotte is a 3rd year DPhil student on a BBSRC industrial CASE project with Johnson Matthey.

Maya Landis

Maya is a DPhil student at Jesus College and is part of the Oxford Inorganic Chemistry for Future Manufacturing CDT (OxICFM), and is jointly supervised by Prof. Nicole Grobert in the Department of Materials. Her research focuses on the implementation of biocatalytic synthesis in flow while exploring carbon nanotube supports. For her undergraduate degree she studied at Barnard College of Columbia University. In her free time, she enjoys gardening, singing with the Jesus College Choir, and occasionally some yoga.

Lucy Browne

Lucy is a second year DPhil student at St Peter's College. She graduated from the University of St Andrews in 2018 with an "MChem with Industrial Placement" - her placement was at Johnson Matthey in Cambridge which involved working on homogeneous hydrogenation of esters. After graduating, Lucy returned to work at Johnson Matthey as a Research Chemist, working on optimising various homogeneous and heterogeneous catalyst systems for commercial customers. Now, in the Vincent group, Lucy is working on the applications of NiFe hydrogenases. In her free time, Lucy enjoys finding new running routes and travelling (when possible!).

Peter Todd

Peter is a first year DPhil student at Hertford College. He carried out his Part II project with the Vincent group on H2-driven biocatalysis for the synthesis of pharmaceutical building blocks, evaluating the substrate scope of two alcohol dehydrogenase enzymes. His DPhil research will investigate the mechanism and applications of a hydrogenase enzyme and the scale up of biocatalytic amino acid syntheses. Outside of the lab, you're likely to find Peter down at Iffley Pool, rowing on the Isis or getting involved in film and musical theatre.

Zehui Duan

Zehui is a first year DPhil student at Jesus College. She is co-supervised by Prof. Vincent and Dr. Patricia Rodríguez Macía. She focuses on using advanced spectroscopy techniques to study the iron-sulfur clusters of FeFe-hydrogenase. She graduated from Imperial College London with a MRes in Plastic Electronic Materials. She got her B.S. in Chemical Engineering in Taiwan and was also an invited student in Chalmers University of Technology (Sweden). In her spare time, she enjoys debating and traveling.

Wong Kin Long (Chris)

I am a first-year DPhil student at Jesus College. I earned my BSc at the University of Hong Kong (HKU). My research focus is related to protein crystallography together with spectroelectrochemical techniques for NiFe hydrogenases.

Jiayu Peng (Adam)

My name is Jiayu Peng; I am the one on the left of the photo and my brother is on the right; we are twins. Before coming to Oxford, I completed my BSc in Pharmaceutical Science at Nanjing Tech University. In my free time I like to play games, basketball, watch some animations and live stream.

Sofia Helin

Sofia is a first year DPhil student at Linacre College on the Interdisciplinary Bioscience DTP. She studied at York for her MChem Industry, with a placement at Oxford NanoSystems. Her project focuses on optimising HydRegen enzyme systems and converting them into flow with industry partner, StoliChem. In her spare time, she enjoys first aid, weightlifting and German.

Part II (MChem) students

Hazel Rycroft

Hazel is a Part II student at Jesus College, and her project involves interfacing nanoparticles with enzymes. In her free time, she enjoys cooking, reading, and spending time outside.

Joe Addy

Joe is a part II student at Worcester College, and his research involves investigating H2 driven flavin recycling for ene-reductase reactions. Outside of work Joe sings with the a cappella group Out of the Blue and plays football along with some very average darts for his College.

Georgia Stonadge

Georgia is a Part II student at Exeter College. Her research investigates the use of hydrogenases as catalysts in the H2-driven production of amine compounds. In her spare time she enjoys rowing and baking.

Zipporah (Zip) Hodder

Zipporah is a Part II student at Worcester College. Her project is developing electrocatalytic NADPH recycling for imine reductases. She likes to dance, spend time with her friends and travel in her free time.

Former Postdocs

2016 to 2021

Jack Rowbotham was a long-serving PDRA on the HydRegen project and has left to take up a BBSRC Discovery Fellowship at the University of Manchester.

to 2021

Holly Reeve wins the prize for longest-serving member of the Vincent group. During her Part II and DPhil research in the group, she developed the HydRegen technology. She then took on a Project Manager / Co-Investigator role on a major 5-year Translation grant from EPSRC/BBSRC/IUK under the Industrial Biotechnology Catalyst scheme to translate the technology to market. Under Holly's expert leadership, this project was a fantastic success, spawning new IP, numerous high-profile publications and new research directions. Near the completion of this project, Holly was accepted onto the iCURE programme, secured R&D funding and spun out the company HydRegen Ltd with Kylie Vincent as co-founder. Holly is now CEO of HydRegen Ltd, located at Begbroke Science Park.

2018-2021

Sarah Cleary joined the Vincent group after a PhD in organic chemistry from the University of Vermont (USA). She helped to bring green chemistry metrics to evaluate our HydRegen catalyst system and to develop new catalytic applications and reaction scale up in batch and flow. She has now moved into a role as Chief Scientific Officer at spin out company, HydRegen Ltd.

2019-2021

Koji Urata is a graduate of Oxford University, and his DPhil was a joint project between the Wong and Vincent groups, specialising in hydrogen driven biocatalysis reactions. Koji rejoined the group in 2019 as a PDRA, after a period working for Hawk-Eye Innovations. Koji has now gone on to Lab Management role.

2020-2021

Michele Ruggeri worked in the Vincent group on translating biocatlaytic processes into flow. He left to take up a postdoctoral position in Europe.

2020-2021

Adrian Barranco was a Postdoc in the group, working on chemo-biocatalysis. He is now a Marketing Officer at Biosynth Carbosynth.

2020

Katrina Madden was a Postdoc in the group, working on biocatalysis for medicinal chemistry. She is now a Newcastle University Academic Track Fellow in Drug Discovery (School of Natural and Environmental Sciences).

2017-2020

Erin Dodd was a Postdoc in the group, working on nitrosylation of iron-sulfur proteins. She is now Assistant Professor of Bioinorganic Chemistry at the Universite du Quebec a Montreal.

2019-2020

Renee Haver worked in the HydRegen team on developing multistep bio- and chemo-bio cascade reactions. She has now gone on to teacher training.

2017-2019

Simone Morra held a Marie Sklodowska-Curie Fellowship and specialised in mechanistic studies of FeFe hydrogenases. In 2020, he was appointed to an independent Fellowship at the University of Nottingham, UK.

2011-2019

Philip Ash was a Postdoc in the group, specialising in spectroelectrochemistry of metalloproteins. In 2019, he was appointed as a Lecturer in the School of Chemistry, University of Leicester, UK.

2015-2017

Simantini Nayak held a Marie Sklodowska-Curie Fellowship and worked on operando infrared studies of the oxygen reduction reaction at supported metal nanoparticle catalyst sites. She then went on to work for ZapGo Ltd., and is now a Scientist at CSIR-IMMT, India.

2014-2016

Matteo Duca held a Marie Curie Fellowship, his research in the Vincent Group was at the interface between metal- and bioelectrocatalysis for the nitrogen and carbon cycles. He is now Development and Scientific Affairs Director at Quebec Centre for Advanced Materials, Canada.

2012

Lars Lauterbach worked on the HydRegen project for H2-driven NADH regeneration during 2012. He now works in the Institute for Chemistry at the Technical University, Berlin, Germany.

Former Research Scientists

2018-2019

Jake Nicholson was a research scientist in the group, specialising in reductive deuteration strategies. In 2019, he started a PhD at King's College London in the group of Dr Alex Brogan.

Former DPhil Students

2021

Barnabas Poznansky (Barney)

2021

Jiaao Wei

2020

Ting Chen

2020

Tianze Zhu

2020

Justin Weeks

2017

Thomas Lonsdale

2017

Kouji Urata

2016

Ricardo Hidalgo Gonzalez

2016

Gary Chang

2015

Ian McPherson

2015

Min-Wen Chung

2015

Jonathan Quinson (joint with Nicole Grobert at Materials)

2015

Holly Reeve

2014

Daniel Grabarczyk

2014

Pathinan Paengnakorn

2013

Adam Healy

2012

Zulkifli Idris

2012

Juan Liu

Former MRes Students

2016

Ceren Zor (joint with Nicole Grobert at Materials)

Former Part II (MChem 4th Year) Students

2020-2021

Yifei (Jefferson) Chen

Amy Lian

Asher Winter

Hannah Taylor

2019-2020

Simona Everts

Nina Jenkins

Sharoon Lassen

Saloni Pun

Peter Todd

2018-2019

Nisa (Raja) Ashman

Amelia Brasnett

Maria Ryan

2017-2018

Jake Nicholson

Ben Rackham

2016-2017

Sophie Kendall-Price

Katherine Page

Rachael Ng

2015-2016

Farieha Altaf

Matthew Burnett

Rebecca Shutt

2014-2015

Michael Ash

Justin Weeks

2013-2014

Benjamin Aucott

Eleanor Hall

Chloe Tomlinson

Ingvild Gudim

2012-2013

Ben Bluestone

Charlie Stevens

Jenny Bradley

Thomas Lonsdale

2011-2012

Tom Lyle

Lucie Dearlove

Thomas Bloomfield

Robert Spence

2010-2011

Charlotte McKenna

Henry Waite

Kate Simpson-Wells

Ian McPherson

2009-2010

Ean Ong

Holly Reeve

2008-2009

Adam Healy

Rachel White