Kylie Vincent's Group
Department of Chemistry,
University of Oxford,
Inorganic Chemistry Laboratory,
South Parks Road, OX1 3QR
kylie.vincent@chem.ox.ac.uk

Kylie Vincent

Professor of Inorganic Chemistry and
Tutorial Fellow in Inorganic Chemistry at Jesus College Oxford

Kylie Vincent is a graduate of the University of Melbourne, Australia (BA/ BSc(Hons), Ph.D. (2004)). Her PhD research was conducted in the group of Stephen Best (University of Melbourne) and involved a 12 month collaborative visit to the group of Chris Pickett (John Innes Centre, Norwich, UK) supported by a Rae and Edith Bennett Travelling Scholarship. She carried out postdoctoral research at the University of Oxford with Fraser Armstrong from 2002-2007 and held an R. J. P. Williams Junior Research Fellowship at Wadham College, Oxford from 2003-2007. In October 2007 she took up a Royal Society University Research Fellowship in the Chemistry Department at Oxford University and a Senior Research Fellowship at Wadham College, Oxford. In October 2008 she was appointed to an RCUK Academic Fellowship in the Chemistry Department and a Senior Research Fellowship at Jesus College Oxford. She was appointed Associate Professor in 2013, and appointed to a full Professorship in 2017. Her research interests include mechanistic studies of small molecule activation in biology, and applications of enzymes in chemical synthesis. She teaches in Inorganic Chemistry. View CV

Postdoctoral Scientists

Holly Reeve (Project Manger, HydRegen)

Holly completed her Part II and DPhil in the group and has been responsible for development of the HydRegen technology. She is now Project Manager and Co-Investigator on the Industrial Biotechnology Catalyst funded project that has been awarded to develop this technology towards commercialisation. Holly has completed a number of business and entrepreneurship training courses to support this work. View CV

Jack Rowbotham

Jack completed his undergraduate degree at the University of Cambridge before moving to Durham for his PhD. His doctoral research with Phil Dyer and Chris Greenwell investigated the coordination chemistry of algal carbohydrates. Jack joined the Vincent group in April 2016 as a PDRA where he is currently working on the optimisation and application of immobilised metalloenzymes as heterogeneous hydrogenation catalysts (see the HydRegen project).

Miguel Ramirez

Miguel is a Postdoctoral Research Associate contributing to the development of the HydRegen technology. He is a graduate of The University of Texas at Austin (BSc) and completed his Ph.D. in Chemical Engineering at Texas A&M University in 2013. Miguel works in the molecular biology and protein engineering efforts required for enzyme preparation, engineering and adaptation to the HydRegen technology. His research interests include the application of proteins for biotechnology and synthetic biology applications.

Sarah Cleary

Sarah completed her undergraduate degree in biochemistry from Bates College (USA), and her PhD in organic chemistry from the University of Vermont (USA) in 2018. She is interested in developing green approaches to synthetic organic methodologies, and joined the HydRegen project in order to help scale up the batch biocatalytic hydrogenation reactions. View CV

Kouji Urata

Koji rejoined the group in May 2019 as a PDRA, from Hawk-Eye Innovations where he most recently served as an Operations Manager for Asia, based in Dubai. Koji is a graduate of Oxford University, and he has also completed DPhil as a joint project in both Wong and Vincent groups, specialising in hydrogen driven biocatalysis reactions. With prior experiences in both SME and academic settings, Koji is currently working in business development and consulting on how to best bring the HydRegen technology into the market. View CV

Rhiannon 'Non' Evans

Non joined the Vincent group in August 2019 as a post-doctoral research associate bringing specialist knowledge of hydrogenases to the group. With expertise in redox enzymes, protein film electrochemistry and molecular biology & genetics, Non is primed to develop the hypotheses around hydrogenase mechanism, coupled with the development of in crystallo IR and spectroelectrochemistry. During her spare time she is actively avoiding injury to be able to one day run a marathon. View CV

Patricia Rodríguez Macía

Patricia did her undergraduate studies in Chemistry at the University of Alicante (Spain) before moving to Germany for her PhD at the Max Planck Institute for Chemical Energy Conversion (MPI-CEC) with Prof. Lubitz. Her doctoral research focused on employing electrochemistry and infrared spectroscopy to perform mechanistic studies on hydrogenases and bio-inspired synthetic catalysts. After completing her PhD, she joined Prof. DeBeer's group at MPI-CEC to work on carbon monoxide dehydrogenases and other metalloenzymes applying X-ray spectroscopy. Patricia joined the Vincent group in January 2020 as a Postdoctoral Research Associate to contribute to optimisation of immobilization approaches for metalloenzymes and to work on the development of infrared spectroelectrochemical techniques. She loves travelling and in her free time she enjoys cooking and meeting with friends.View CV

Tim Sudmeier

Katrina Madden

Kate completed her undergraduate degree at Durham University, spending a year in industry at AstraZeneca within R&D Oncology. She then stayed on in Durham to complete her PhD with Professor Andy Whiting in the synthesis of polyene natural products, where she used palladium cross-coupling chemistry to make unstable antioxidant bacterial pigments. She then moved to work as a Postdoctoral Associate in Medicinal Chemistry in January 2017 at Oxford, co-supervised by Professor Angela Russell and Professor Steve Davies. During this time she worked on phenotypic drug discovery projects focussing on controlling stem cell fate in the blood and in the brain, for applications in leukaemia and neurodegenerative disease. Within the Vincent group, she aims to apply the HydRegen technology to medicinally relevant molecules, specifically to establish the substrate scope of the technology and generate new deuterium-labelled drug-like molecules.View CV

Adrian Barranco

Adrian studied Chemistry at the University of Alicante (Spain). He then moved to Germany where he spent a year working in a composite materials company before studying for his Master's. After that, he started his PhD at the Heterogeneous Catalysis Department of Prof. Schuth, under Dr. Felderhoff's supervision. His doctoral studies focused on the synthesis of aluminium-based metal hydrides via mechanochemical methods and its applicability as selective reducing agents for organic reduction reactions in greener and mild conditions. Here, he will work on methods for combining metal and enzyme catalysts as part of the HydRegen project. During his free time, he likes cooking and meeting friends. And if you cannot find him, he is most probably busy playing football that is one of his passions.

DPhil and MSc Students

Michael Posidias

Michael is a 4th year DPhil student at Jesus College. His research involves novel biocatalytic approaches to NAD+ recycling for selective oxidation of primary alcohols to aldehydes. The project includes a collaboration with Johnson Matthey Catalysis and Chiral Technologies and is funded by the BBSRC Industrial CASE Studentship scheme. Before coming to Oxford, Michael received his MChem in Chemistry with Forensic Science at the University of Leicester in July 2015. In his free time, he enjoy watching sports and films, especially psychological thrillers!

Sophie Kendall-Price

Sophie (former Part II) is a 2nd year DPhil student at Christ Church. Her research involves the use of infrared spectroelectrochemical techniques in mechanistic studies of NiFe hydrogenases. In her free time, Sophie enjoys playing the double bass, eating Korean food and hiking around the countryside with her dog.

Xu Zhao

Xu Zhao is a 2nd year DPhil student at Exeter College. His work includes but not limited to the application of oxidoreductase and research towards scale-up of the Vincent group's HydRegen technology. He got his bachelor degree in chemical engineering at China University of Petroleum (Beijing, China) and his master degree at University of British Columbia (Canada).

Jiaao Wei

I am a 2nd year DPhil student at Merton college. I got my bachelor degree from Beijing University of Chemical Technology and University of Birmingham. My research in the Vincent group is about the mechanistic studies of NiFe hydrogenase enzymes and understanding efficient H2 oxidation in biology. In my spare time, I like to travel and do some sport and enjoy life in the UK.

Jiawen Zhang

Jiawen Zhang is a 2nd year DPhil student at Jesus College. His research involves the mechanisms of biocatalytic carbon dioxide reduction. He got his bachelor degree at Tsinghua University, and he got his master degree at University of Sheffield. In his free time, he loves basketball and PC gaming!

Barnabas Poznansky

Barnabas is a DPhil student at St Hugh's College. His research focuses on the use of the HydRegen technology in flow. Barnabas graduated from the University of Warwick in July 2017 with an MChem in Chemistry with Professional Experience. His MChem dissertation focused on the enantioselective synthesis of β-lactones with quinine derived catalysts.

Yu Sun

Shiny Joseph Srinivasan

I am a second year DPhil student at St. Edmund Hall. I received my bachelor's degree in Chemistry from PSG College of Arts and Science, India and then completed my Masters in Chemistry from the National Institute of Technology, Trichy (India). In the Vincent group, I am working in the HydRegen project trying to efficiently recycle the biologically important cofactors in order to be used for industrially significant enzymatic chemical conversions. In my free time, I love to dance, travel and explore new places.

Wangzhe Li

Wangzhe is a 2rd year DPhil student at Lincare College and he completed his BSc degree at Durham University. His research in the Vincent group involves studying NiFe hydrogenases via spectroelectrochemical methods.

Sam (Tin) Lai

Sam is a 1st year DPhil student whose research focuses on the mechanistic study of [FeFe] Hydrogenase. He got his bachelor degree from Durham University. He loves to play basketball in his free time.

Charlotte Hancox

Charlotte is a 1st year DPhil student supervised jointly by Holly Reeve and Kylie Vincent.

Amelia Brasnett

Amelia is a 1st year DPhil student carrying out a 3-month rotation project for the Interdisciplinary Bioscience DTP in the Vincent group.

Part II (MChem) students

Simona Everts

Simona is a Part II student at Balliol college. Her research focuses on mechanistic studies of biological carbon dioxide fixation. In her spare time she enjoys travelling and playing different sports.

Nina Jenkins

Nina is a current Part II student at Keble College. Her research is looking into selective reduction of azides and nitro groups. In her spare time, she plays rugby for the university team.

Sharoon Lassen

Sharoon is a Part II (MChem) student at St Hugh's College. Her research in the Vincent Group focuses on heterogeneous catalysis for cascade reactions in continuous flow reactors. During her spare time she enjoys exploring new places and photography!

Saloni Pun

Saloni is a Part II student from St Hilda's college. Her research focuses on exploring the use of HydRegen system for reductive amination. In her spare time, she likes to write/read poetry and take long walks in nature!

Peter Todd

Peter is a Part II (MChem) student at Jesus College. His research project focuses on the use of biocatalysis - specifically H2-driven, NADH-dependent enzyme systems - for producing pharmaceutical building blocks in collaboration with the Russell Group. Outside of the lab, you're bound to find him in the pool, rowing or playing badminton. He also has a keen interest in music and film, so be sure to send any recommendations his way!

Former Postdocs

2017-2020

Erin Dodd was a Postdoc in the group, working on nitrosylation of iron-sulfur proteins. She is now Assistant Professor of Bioinorganic Chemistry at the Universite du Quebec a Montreal. .

2019-2020

Renee Haver worked in the HydRegen team on developing multistep bio- and chemo-bio cascade reactions. She has now gone on to teacher training.

2017-2019

Simone Morra held a Marie Sklodowska-Curie Fellowship and specialised in mechanistic studies of FeFe hydrogenases. In 2020, he was appointed to an independent Fellowship at the University of Nottingham.

2011-2019

Philip Ash was a Postdoc in the group, specialising in spectroelectrochemistry of metalloproteins. In 2019, he was appointed as a Lecturer in the School of Chemistry, University of Leicester.

2015-2017

Simantini Nayak held a Marie Sklodowska-Curie Fellowship and worked on operando infrared studies of the oxygen reduction reaction at supported metal nanoparticle catalyst sites. She then went on to work for ZapGo Ltd.

2014-2016

Matteo Duca held a Marie Curie Fellowship, his research in the Vincent Group was at the interface between metal- and bioelectrocatalysis for the nitrogen and carbon cycles. He is now employed as the Development and Scientific Affairs Director at Quebec Centre for Advanced Materials in Canada.

2012

Lars Lauterbach worked on the HydRegen project for H2-driven NADH regeneration during 2012. He now works in the Institute for Chemistry at the Technical University, Berlin, Germany.

Former Research Scientists

2018-2019

Jake Nicholson was a research scientist in the group, specialising in reductive deuteration strategies. In 2019, he started a PhD at King's College London in the group of Dr Alex Brogan.

Former DPhil Students

2020

Ting Chen

2020

Tianze Zhu

2020

Justin Weeks

2017

Thomas Lonsdale

2017

Kouji Urata

2016

Ricardo Hidalgo Gonzalez

2016

Gary Chang

2015

Ian McPherson

2015

Min-Wen Chung

2015

Jonathan Quinson (joint with Nicole Grobert at Materials)

2015

Holly Reeve

2014

Daniel Grabarczyk

2014

Pathinan Paengnakorn

2013

Adam Healy

2012

Zulkifli Idris

2012

Juan Liu

Former MRes Students

2016

Ceren Zor (joint with Nicole Grobert at Materials)

Former Part II (MChem 4th Year) Students

2018-2019

Nisa (Raja) Ashman

Amelia Brasnett

Maria Ryan

2017-2018

Jake Nicholson

Ben Rackham

2016-2017

Sophie Kendall-Price

Katherine Page

Rachael Ng

2015-2016

Farieha Altaf

Matthew Burnett

Rebecca Shutt

2014-2015

Michael Ash

Justin Weeks

2013-2014

Benjamin Aucott

Eleanor Hall

Chloe Tomlinson

Ingvild Gudim

2012-2013

Ben Bluestone

Charlie Stevens

Jenny Bradley

Thomas Lonsdale

2011-2012

Tom Lyle

Lucie Dearlove

Thomas Bloomfield

Robert Spence

2010-2011

Charlotte McKenna

Henry Waite

Kate Simpson-Wells

Ian McPherson

2009-2010

Ean Ong

Holly Reeve

2008-2009

Adam Healy

Rachel White