Dr Lisa A. Thompson
My research interests include the translation of chemo and biocatalytic processes into continuous flow reactors, with an emphasis on heterogeneous catalysis. My current role involves the development of the HydRegen technology in a range of multiphasic flow reactors.
lisa.thompson@chem.ox.ac.uk
Current Position
| April 2017 - | Postdoctoral Research Associate in Flow Chemistry Vincent Group, Department of Chemistry, University of Oxford |
| Education | |
| 2013 - 2017 | PhD (Chemistry) Chemo- and Biocatalysis for the Synthesis of Chiral Amines in Continuous Flow Reactors, Institute of Process Research and Development, University of Leeds, UK (with Prof. A. John Blacker, Dr Richard A. Bourne and Prof. Nicholas J. Turner) |
| 2009 - 2013 | MChem (Hons) First Class, University of Edinburgh, UK |
| Public Engagement and Outreach Events | |
| Feb 2019 & 2018 | Women in Science Taster Day, Jesus College, Oxford, UK |
| Feb 2018 | EPSRC Science for a Successful Nation, London, UK |
| Nov 2017 | Oxford Sparks LIVE event, Oxford, UK |
| Sept 2017 | Curiosity Carnival (European Researchers' Night), Oxford, UK |
| Funding | |
| 2018 | Supervisor and Principal Investigator: Development of Public Engagement with Research Activities Undergraduate Bursary Award (Summer student project) |
| 2017 | Travel: BBSRC Innovation Travel Fund |
| Publications | |
| Thompson, L.A., Rowbotham, J.S., Nicholson, J.H., Ramirez, M.A., Zor, C., Reeve, H.A., Grobert, N., Vincent, K.A., 'Rapid, Heterogeneous Biocatalytic Hydrogenation and Deuteration in a Continuous Flow Reactor', ChemCatChem, accepted | |
| B. Poznansky, L.A. Thompson, S.A. Warren, H.A. Reeve, K.A. Vincent, 'Carbon as a Simple Support for Redox Biocatalysis in Continuous Flow', Org. Process Res. Dev., 2020, Special Issure: Flow Chemistry Enabling Efficient Synthesis. DOI: 10.1021/acs.oprd.9b00410 | |
| Thompson, L.A., Rowbotham, J.S., Reeve, H.A., Zor, Z., Grobert, N., Vincent, K.A., Chapter 18: Biocatalytic Hydrogenations on Carbon Supports in 'Nanoarchitectures Built with Carbon Nanotubes and Magnetic Nanoparticles', 2020, Methods in Enzymology, Editor - Kumar, Volume 630, accepted, Link | |
| Cover Article: C. Zor, H. A. Reeve, J. Quinson, L. A. Thompson, T. H. Lonsdale, F. Dillon, N. Grobert and K. A. Vincent, H2-Driven biocatalytic hydrogenation in continuous flow using enzyme-modified carbon nanotube columns, Chem. Commun., 2017, 53, 9839 - 9841, DOI:10.1039/C7CC04465H | |
| M. R. Chapman, M. H. T. Kwan, G. King, K. E. Jolley, M. Hussain, S. Hussain, I. E. Salama, C. Gonzalez Nino, L. A. Thompson, M. E. Bayana, A. D. Clayton, B. N. Nguyen, N. J. Turner, N. Kapur, and A. J. Blacker, Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times, Org. Process. Res. Dev., 2017, 21, 1294 - 1301, DOI:10.1021/acs.oprd.7b00173 | |
| K. G. Hugentobler, M. Rasparini, L. A. Thompson, K. E. Jolley, A. J. Blacker and N. J. Turner, Comparison of a batch and flow approach for the lipase catalysed resolution of a cyclopropanecarboxylate ester; a key building block for the synthesis of ticagrelor, Org. Process. Res. Dev., 2017, 21, 195 - 199, DOI:10.1021/acs.oprd.6b00346 | |
| S. Doherty, J. G. Knight, M. A. Carroll, A. R. Clemmet, J. R. Ellison, T. Backhouse, N. Holmes, L. A. Thompson and R. A. Bourne, Efficient and selective oxidation of sulfides in batch and continuous flow using styrene-based polymer immobilised ionic liquid phase supported peroxotungstates, RSC Adv., 2016, 6, 73118 - 73131, DOI:10.1039/C6RA11157B | |
| Conference Presentations | |
| July 2019 | 14th International Symposium on Biocatalysis and Biotransformations (BioTrans 2019), Groningen, Netherlands (Poster Prize) |
| May 2019 | RSC/SCI Continuous Flow Technology IV Conference, Manchester, UK (Oral) |
| Dec 2018 | 5th Winter Process Chemistry Conference, Manchester, UK (1st Place Poster Prize) |
| Dec 2017 | RSC Biotransformations: From Science to Industrial Applications Symposium, London, UK (Poster) |
| July 2017 | Biotransformations 2017 Summer School, Hannover, Germany (Oral + Poster) |
| Sept 2016 | AstraZeneca CASE Student Symposium, Macclesfield, UK (Oral + Poster) |
| March 2016 | 251st ACS National Meeting, San Diego, USA (Oral) |
| Oct 2015 | 5th Frontiers in Organic Synthesis Technology Conference, Hungary (Poster) |
| Sept 2015 | 5th Northern Sustainable Chemistry Postgraduate Symposium, University of York, UK (Poster) |
| Dec 2014 | 2nd Winter Process Chemistry Conference, University of Manchester, UK (Poster) |